Trisodium Citrate Anhydrous

Product Data

Trisodium Citrate Anhydrous (CAS No. 68-04-2) is a white, crystalline powder known for its excellent buffering capacity, solubility, and chelating properties. As a leading manufacturer and supplier, Dr. Paul Lohmann^® provides high-purity Trisodium Citrate Anhydrous for pharma and food applications. Our products are manufactured under stringent quality control to meet global regulatory standards and specific customer requirements.

General Characteristics

Synonyms: Sodium Citrate, tertiary

Formula	C₆H₅Na₃O₇
Molecular weight	258.07 g/mol
CAS No.:	68-04-2
EINECS No.:	200-675-3
HS No.:	29181500

Product number	Product parameter	Storage conditions \| Retest period	Additional information
502010002	crystalline powder USP-NF \| NF 2024 \| E 331 (iii) \| FCC 14 27.0 % Na \|	Keep well closed, dry and at room temperature; 24 months	API documentation available
502010004	fine powder USP-NF \| NF 2024 27.0 % Na \|	Keep well closed, dry and at room temperature; 24 months
502010005	fine granules USP-NF \| NF 2024 27.0 % Na \|	Keep well closed, dry and at room temperature; 24 months	API documentation available

++ > 100 g/l | + 10 - 100 g/l | − 1 - 10 g/l | −− < 1 g/l
The solubility specified here was measured in water. The solubility is influenced by many factors in the application.

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Benefits of Trisodium Citrate Anhydrous (CAS No. 68-04-2)

Choosing our Trisodium Citrate Anhydrous offers distinct advantages:

High chemical purity and consistent quality
Excellent solubility in water and fast dissolution rate
Versatile functionality as buffering agent, complexing agent, and emulsifier
Customizable particle size distributions for diverse applications
Produced in Germany under certified GMP and food-grade standards
Low endotoxin and microbiological levels for pharmaceutical and biotech uses

Why Choose Dr. Paul Lohmann^® as Your Trisodium Citrate Anhydrous Supplier?

With over 135 years of experience in producing specialty Mineral Salts, we stand for:

Tailor-made product specifications to suit your process
In-house R&D and application support for custom formulations
Reliable global logistics and supply chain
Transparent documentation and regulatory expertise
Responsive B2B customer service from our Emmerthal headquarters

Contact Us for More Information on Trisodium Citrate Anhydrous

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Application Areas

Trisodium Citrate Anhydrous is widely used across various B2B sectors:

Pharmaceutical Applications

In the pharmaceutical industry, Trisodium Citrate Anhydrous is widely used for its excellent buffering capacity and chemical stability. It plays a crucial role in both intravenous and oral drug formulations by maintaining the desired pH level and enhancing the bioavailability of active ingredients. Additionally, it serves as an effective anticoagulant in blood preservation solutions and dialysis treatments due to its ability to bind calcium ions and prevent clotting. Trisodium Citrate is also utilized in topical medications, where it stabilizes formulations and extends product shelf life. Unlike the dihydrate form, the anhydrous variant contains no crystal water, offering a higher active content per gram and a lower moisture profile. This makes it particularly suitable for dry or moisture-sensitive preparations, such as effervescent powders, dry blends, and tablets. Thanks to its high purity and compliance with pharmaceutical-grade standards, the product from Dr. Paul Lohmann^® is ideally suited for demanding applications in both human and veterinary medicine.

Food & Beverage Applications

Trisodium Citrate Anhydrous, designated as E331(iii), is widely used in the food and beverage industry due to its versatility. Its functions include serving as a buffering agent, acidity regulator, emulsifier, flavor enhancer, and sequestrant. Trisodium Citrate also plays a key role in processed cheese and dairy products, where it improves texture and prevents phase separation during melting. Moreover, it enhances flavor perception by balancing acidity and masking undesirable off-notes. The anhydrous form is particularly advantageous in moisture-sensitive products such as powdered formula, instant beverages, and other dry mixes, where low moisture content is critical for product stability and shelf life. Trisodium Citrate Anhydrous is also a preferred ingredient as an electrolyte in isotonic powder beverages, contributing to proper hydration and mineral balance.

The information given on this Website corresponds to our current knowledge. We warrant in the frame of our General Terms and Conditions of Sale that our products are manufactured in accordance with the specifications. However, we disclaim any liability with regard to the suitability of our products for a particular purpose or application or their compatibility with other substances. Tests have to be performed by the customer who also bears the risk in this respect. Nothing herein shall be construed as a recommendation to use our products in conflict with third parties' rights.